30 سپتامبر 2025, مقالات ISI
This systematic review and meta-analysis of randomized controlled trials (RCTs) sought to evaluate the effects of Nigella sativa (N. sativa) consumption on glycemic index in adults. A systematic literature search up to December 2023 was completed in PubMed, Scopus, and Web of Science, to identify eligible RCTs. Random effects models were assessed based on the heterogeneity tests, and pooled data were determined as weighted mean differences with a 95 % confidence interval. Finally, a total of 30 studies were found to be eligible for this meta-analysis. The pooled results using random effects model indicated that N. sativa supplementation significantly reduced FBS (SMD: −1.71; 95 % CI: −2.11, −1.31, p <0.001; I2= 92.7 %, p-heterogeneity <0.001) and HA1c levels (SMD: −2.16; 95 % CI: –3.04, −1.29, p <0.001; I2= 95.7 %, p-heterogeneity <0.001) but not effect on insulin (SMD = 0.48; 95 % CI: −0.53, 1.48, P = 0.353; I2= 96.1 %, p-heterogeneity <0.001), and HOMA-IR (SMD: −0.56; 95 % CI: −1.47, 0.35, p=0.229; I2= 95.0 %, p-heterogeneity <0.001).Overall, the evidence supports the consumption of N. sativa to reduce FBS and HA1c levels. Additional research, featuring extended durations and robust study designs, is necessary to determine the ideal dosage and duration of N. sativa supplementation for achieving a positive impact on glycemic markers.
Ginseng supplementation may improve inflammatory profiles and support cardiometabolic health, according to a comprehensive review of 44 randomized controlled trials.
Nigella sativa supplementation significantly improves lipid profiles in adults by lowering TC, TG, LDL-C, and raising HDL-C, supporting its role as an adjuvant anti-hyperlipidemic agent.
Most Iranian hospital pharmacies fall short of age-friendly criteria, stressing the urgency for policy and system reforms to meet elderly patients’ needs.
Curcumin supplementation appears to alleviate anxiety symptoms, but more high-quality trials are needed to confirm its clinical effectiveness.
Ghee may support bone and joint health through fatty acids and vitamins that reduce inflammation, enhance bone density, and improve joint lubrication.
Glucomannan supplementation reduces total cholesterol and LDL-C in adults, with no significant effects on TG, HDL-C, or Apo A1 levels
Berberine supplementation shows significant benefits in improving lipid profile (reducing LDL-C, TC, TG, and increasing HDL-C) and waist circumference, though its effects on overall obesity indices remain inconclusive.
An Evidence-Based Review on Wound Healing Herbal Remedies From Reports of Traditional Persian Medicine
A scientific report on a novel herbal cream for skin wound healing, combining traditional Persian botanical knowledge with modern pharmaceutical research.
This umbrella and systematic review with meta-analysis evaluates the efficacy and safety of imeglimin for type 2 diabetes, showing significant improvements in glycemic control and beta-cell function.
This meta-analysis evaluates how walnut intake influences key oxidative stress biomarkers, highlighting increased catalase activity with no significant changes in other markers.
